Remco L.A de Vrueh: search on Z-Library

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1

Deal watch: Roles and strategies for health foundations in public–private partnerships

de Vrueh, Remco L., Awad, Waseem, Stolk, Anne, Dijcks, Fred A., Rijnders, Ton W.M., Janssen, Jorg W.

Journal:

Nature Reviews Drug Discovery

Year:

2014

Language:

english

File:

PDF, 596 KB

english, 2014

2

Does market exclusivity hinder the development of Follow-on Orphan Medicinal Products in Europe?

Anne EM Brabers, Ellen HM Moors, Sonja van Weely, Remco LA de Vrueh

Journal:

Orphanet Journal of Rare Diseases

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

3

Drug development for exceptionally rare metabolic diseases: challenging but not impossible

Putzeist, Michelle, Mantel-Teeuwisse, Aukje K, Wied, Christine C Gispen-de, Hoes, Arno W, Leufkens, Hubert GM, de Vrueh, Remco LA

Journal:

Orphanet Journal of Rare Diseases

Year:

2013

Language:

english

File:

PDF, 265 KB

english, 2013

4

Towards harmonization of outcome measures in children with mitochondrial disorders

Koene, Saskia, Jansen, Merel, Verhaak, Chris M., de Vrueh, Remco L.A., de Groot, Imelda J.M., Smeitink, Jan A.M.

Journal:

Year:

2013

Language:

english

File:

PDF, 49 KB

english, 2013

5

Translation of rare disease research into orphan drug development: disease matters

Harald E. Heemstra, Sonja van Weely, Hans A. Büller, Hubert G.M. Leufkens, Remco L.A. de Vrueh

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 399 KB

english, 2009

6

Conjugation of Oligonucleotides with Steroid Structures and Their Interaction with the Low-Density Lipoprotein

Rump, Erik T., de Vrueh, Remco L.A., Biessen, Erik A.L., van Berkel, Theo J.C., Bijsterbosch, Martin K.

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 191 KB

english, 1997

7

Product development programs for neglected tropical diseases: A crucial role for expert meetings

Hussaarts, Leonie, van der Weijde, Kim, Dome, Pierre, Kourany-Lefoll, Elly, Reinhard-Rupp, Jutta, de Vrueh, Remco, Flisser, Ana

Journal:

PLoS Neglected Tropical Diseases

Year:

2017

Language:

english

File:

PDF, 490 KB

english, 2017

8

Modification of the plasma clearance and liver uptake of steroid ester-conjugated oligodeoxynucleotides by association with (lactosylated) low-density lipoprotein

Erik T Rump, Remco L.A de Vrueh, Muthiah Manoharan, Ingrid H.E Waarlo, Richard van Veghel, Erik A.L Biessen, Theo J.C van Berkel, Martin K Bijsterbosch

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 541 KB

english, 2000

9

Targeting Hepatitis B Therapy to the Liver

Dr Patrick C. N. Reusen,Remco L. A. de Vrueh…

Journal:

Clinical Pharmacokinetics

Year:

1996

Language:

english

File:

PDF, 3.92 MB

english, 1996

10

Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting

Patrick C.N Rensen, Remco L.A de Vrueh, Johan Kuiper, Martin K Bijsterbosch, Erik A.L Biessen, Theo J.C van Berkel

Journal:

Advanced Drug Delivery Reviews

Year:

2001

Language:

english

File:

PDF, 922 KB

english, 2001

11

Synthesis of a Lipophilic Prodrug of 9-(2-Phosphonylmethoxyethyl)adenine (PMEA) and Its Incorporation into a Hepatocyte-Specific Lipidic Carrier

Remco L. A. de Vrueh, Erik T. Rump, Leo A. J. M. Sliedregt, Erik A. L. Biessen, Theo J. C. van Berkel, Martin K. Bijsterbosch

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.44 MB

1999

12

Predictors of orphan drug approval in the European Union

Harald E. Heemstra, Remco L. de Vrueh, Sonja van Weely, Hans A. Büller, Hubert G. M. Leufkens

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 158 KB

english, 2008

13

Cryopreservation Enables Long-Term Storage of 9-(2-Phosphonylmethoxy-ethyl) Adenine Prodrug-Loaded Reconstituted Lactosylated High-Density Lipoprotein

Remco L. A. de Vrueh, Theo J. C. van Berkel, Martin K. Bijsterbosch

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 169 KB

english, 2001

14

Preparation of Conjugates of Oligodeoxynucleotides and Lipid Structures and Their Interaction with Low-Density Lipoprotein

Rump, Erik T., de Vrueh, Remco L. A., Sliedregt, Leo A. J. M., Biessen, Erik A. L., van Berkel, Theo J. C., Bijsterbosch, Martin K.

Journal:

Bioconjugate Chemistry

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

15

Lipophilic Derivatization of the Antiviral Drug 9-(2-Phosphonylmethoxyethyl)adenine and Its Incorporation into a Lactosylated Lipid Carrier to Improve Its Liver Uptake

de Vrueh, Remco L.A., Rump, Erik T., Biessen, Erik A.L., Balzarini, Jan, van Berkel, Theo J.C., Bijsterbosch, Martin K.

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 191 KB

english, 1997

16

Selection of development candidates based on in vitro permeability measurements

Chao-Pin Lee, Remco L.A. de Vrueh, Philip L. Smith

Journal:

Advanced Drug Delivery Reviews

Year:

1997

Language:

english

File:

PDF, 1.45 MB

english, 1997

17

Safety-Related Regulatory Actions for Orphan Drugs in the US and EU

Harald E. Heemstra, Thijs J. Giezen, Dr Aukje K. Mantel-Teeuwisse, Remco L. A. de Vrueh, Hubert G. M. Leufkens

Journal:

Year:

2010

Language:

english

File:

PDF, 230 KB

english, 2010

18

Modification of a Phosphorothioate Oligonucleotide with Cholesterol Induces Association of the Oligonucleotide to Serum Lipoproteins and Affects Its Biological Fate

Bijsterbosch, Martin K., Manoharan, Muthiah, Tivel, Kathleen L., Rump, Erik T., Biessen, Erik A.L., De Vrueh, Remco L.A., Cook, P. Dan, van Berkel, Theo J.C.

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 224 KB

english, 1997

19

Towards the harmonization of outcome measures in children with mitochondrial disorders

Koene, Saskia, Jansen, Merel, Verhaak, Chris M, De Vrueh, Remco LA, De Groot, Imelda JM, Smeitink, Jan AM

Journal:

Developmental Medicine & Child Neurology

Year:

2013

Language:

english

File:

PDF, 262 KB

english, 2013

20

Editorial: Public-Private Partnerships as Drivers of Innovation in Healthcare

de Vrueh, Remco L. A., de Vlieger, Jon S. B., Crommelin, Daan J. A.

Journal:

Frontiers in Medicine

Year:

2019

File:

PDF, 728 KB

2019

21

5′-Amino Acid Esters of Antiviral Nucleosides, Acyclovir, and AZT Are Absorbed by the Intestinal PEPT1 Peptide Transporter

Hyo-kyung Han, Remco L. A. de Vrueh, Julie K. Rhie, Kuang-Ming Y. Covitz, Philip L. Smith, Chao-Pin Lee, Doo-Man Oh, Wolfgang Sadee, Gordon L. Amidon1

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 489 KB

1998

22

Orphan drug development across Europe: bottlenecks and opportunities

Harald E. Heemstra, Remco L.A. de Vrueh, Sonja van Weely, Hans A. Büller, Hubert G.M. Leufkens

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

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